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BDBM50112040 4-Amino-N-{1-[1-(3-amino-propyl)-piperidin-4-ylmethyl]-piperidin-4-yl}-5-chloro-2-methoxy-benzamide::CHEMBL174935

SMILES: COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CC2CCN(CCCN)CC2)CC1

InChI Key: InChIKey=DMUBQZCKFYYDBF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50112040   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
HTR4


(GUINEA PIG)		BDBM50112040
PNG
(4-Amino-N-{1-[1-(3-amino-propyl)-piperidin-4-ylmet...)
Show SMILES COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CC2CCN(CCCN)CC2)CC1
Show InChI InChI=1S/C22H36ClN5O2/c1-30-21-14-20(25)19(23)13-18(21)22(29)26-17-5-11-28(12-6-17)15-16-3-9-27(10-4-16)8-2-7-24/h13-14,16-17H,2-12,15,24-25H2,1H3,(H,26,29)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 13n/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against 5-hydroxytryptamine 4 receptor of guinea pig striatum using [3H]-GR-113,808 as radioligand

Bioorg Med Chem Lett 12: 967-70 (2002)


BindingDB Entry DOI: 10.7270/Q2RF5TB7
More data for this
Ligand-Target Pair