BDBM50112134 CHEMBL3609862

SMILES: NC(=O)C12CC3CC(C1)[C@H](NS(=O)(=O)c1ccccc1F)C(C3)C2

InChI Key: InChIKey=WWZPBPZNLUCGFA-CMVNQHTFSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50112134   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50112134 (CHEMBL3609862) Show SMILES NC(=O)C12CC3CC(C1)[C@H](NS(=O)(=O)c1ccccc1F)C(C3)C2 |r,wD:9.10,TLB:8:3:22:6.7.9,10:9:22:23.4.3,THB:4:5:9:23.3.8,4:3:22.5.6:9,8:7:22:23.4.3,1:3:22:6.7.9,1:3:22.5.6:9,(3.58,2.29,;3.07,1.17,;3.79,.17,;1.56,1.02,;1.56,2.59,;.12,3.07,;-1,2.05,;-.95,.32,;.56,-.22,;-2.19,-.22,;-3.39,-1.17,;-4.82,-.59,;-4.99,.63,;-3.85,.17,;-6.03,-1.55,;-5.81,-3.07,;-7.02,-4.02,;-8.45,-3.45,;-8.67,-1.93,;-7.46,-.97,;-7.63,.25,;-1.2,1.02,;-1.2,2.69,;.34,.44,)| Show InChI InChI=1S/C17H21FN2O3S/c18-13-3-1-2-4-14(13)24(22,23)20-15-11-5-10-6-12(15)9-17(7-10,8-11)16(19)21/h1-4,10-12,15,20H,5-9H2,(H2,19,21)/t10?,11?,12?,15-,17?	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	244	n/a	n/a	n/a	n/a	n/a	n/a
Incheon National University Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD1				Bioorg Med Chem Lett 25: 3501-6 (2015) BindingDB Entry DOI: 10.7270/Q2BP04KW
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50112134 (CHEMBL3609862) Show SMILES NC(=O)C12CC3CC(C1)[C@H](NS(=O)(=O)c1ccccc1F)C(C3)C2 |r,wD:9.10,TLB:8:3:22:6.7.9,10:9:22:23.4.3,THB:4:5:9:23.3.8,4:3:22.5.6:9,8:7:22:23.4.3,1:3:22:6.7.9,1:3:22.5.6:9,(3.58,2.29,;3.07,1.17,;3.79,.17,;1.56,1.02,;1.56,2.59,;.12,3.07,;-1,2.05,;-.95,.32,;.56,-.22,;-2.19,-.22,;-3.39,-1.17,;-4.82,-.59,;-4.99,.63,;-3.85,.17,;-6.03,-1.55,;-5.81,-3.07,;-7.02,-4.02,;-8.45,-3.45,;-8.67,-1.93,;-7.46,-.97,;-7.63,.25,;-1.2,1.02,;-1.2,2.69,;.34,.44,)| Show InChI InChI=1S/C17H21FN2O3S/c18-13-3-1-2-4-14(13)24(22,23)20-15-11-5-10-6-12(15)9-17(7-10,8-11)16(19)21/h1-4,10-12,15,20H,5-9H2,(H2,19,21)/t10?,11?,12?,15-,17?	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Incheon National University Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1				Bioorg Med Chem Lett 25: 3501-6 (2015) BindingDB Entry DOI: 10.7270/Q2BP04KW
					More data for this Ligand-Target Pair