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SMILES: F[C@H]1CN(CCn2c3cc(Oc4ccon4)cnc3ccc2=O)CC[C@H]1NCc1ccc2OCC(=O)Nc2n1

InChI Key: InChIKey=NRWKEMOZVPFPJY-RBUKOAKNSA-N

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50112264   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))		BDBM50112264
PNG
(CHEMBL3608756)
Show SMILES F[C@H]1CN(CCn2c3cc(Oc4ccon4)cnc3ccc2=O)CC[C@H]1NCc1ccc2OCC(=O)Nc2n1 |r|
Show InChI InChI=1S/C26H26FN7O5/c27-18-14-33(7-5-19(18)28-12-16-1-3-22-26(30-16)31-23(35)15-37-22)8-9-34-21-11-17(39-24-6-10-38-32-24)13-29-20(21)2-4-25(34)36/h1-4,6,10-11,13,18-19,28H,5,7-9,12,14-15H2,(H,30,31,35)/t18-,19+/m0/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of human ERG by IonWorks assay

ACS Med Chem Lett 6: 741-6 (2015)


BindingDB Entry DOI: 10.7270/Q2PZ5BMK
More data for this
Ligand-Target Pair