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BDBM50112396 5-{(2Z)-2-[[(E)-(4-cyclohexylphenyl)diazenyl](phenyl)methylene]hydrazino}-1-phenyl-1H-tetrazole::CHEMBL23068

SMILES: C1CCC(CC1)c1ccc(NN=C(N=Nc2nnnn2-c2ccccc2)c2ccccc2)cc1

InChI Key: InChIKey=HLTNCPBTMVJHNA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50112396   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Endothelin-converting enzyme 1 (ECE)


(Rattus norvegicus (Rat))		BDBM50112396
PNG
(5-{(2Z)-2-[[(E)-(4-cyclohexylphenyl)diazenyl](phen...)
Show SMILES C1CCC(CC1)c1ccc(NN=C(N=Nc2nnnn2-c2ccccc2)c2ccccc2)cc1 |w:13.13,11.11|
Show InChI InChI=1S/C26H26N8/c1-4-10-20(11-5-1)21-16-18-23(19-17-21)27-28-25(22-12-6-2-7-13-22)29-30-26-31-32-33-34(26)24-14-8-3-9-15-24/h2-3,6-9,12-20,27H,1,4-5,10-11H2
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PC sid
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PubMed
n/an/a 3.60E+3n/an/an/an/an/an/a



Sumitomo Pharmaceuticals Co., Ltd.

Curated by ChEMBL


Assay Description
Tested in vitro for inhibition of Endothelin-converting enzyme (ECE) of rat lung membrane

Bioorg Med Chem Lett 12: 1275-8 (2002)


BindingDB Entry DOI: 10.7270/Q2R49RBT
More data for this
Ligand-Target Pair