null

SMILES: COc1cc(NC(=O)C(=O)NC(C)(C)C)ccc1-c1cnco1

InChI Key: InChIKey=CZCALUZQCFVOLX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50112565   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50112565 (CHEMBL25138 | N-tert-Butyl-N'-(3-methoxy-4-oxazol-...) Show SMILES COc1cc(NC(=O)C(=O)NC(C)(C)C)ccc1-c1cnco1 Show InChI InChI=1S/C16H19N3O4/c1-16(2,3)19-15(21)14(20)18-10-5-6-11(12(7-10)22-4)13-8-17-9-23-13/h5-9H,1-4H3,(H,18,20)(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Inosine-5'-monophosphate dehydrogenase 2				Bioorg Med Chem Lett 12: 1323-6 (2002) BindingDB Entry DOI: 10.7270/Q2NG4PX7
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 1/2 (Homo sapiens (Human))	BDBM50112565 (CHEMBL25138 | N-tert-Butyl-N'-(3-methoxy-4-oxazol-...) Show SMILES COc1cc(NC(=O)C(=O)NC(C)(C)C)ccc1-c1cnco1 Show InChI InChI=1S/C16H19N3O4/c1-16(2,3)19-15(21)14(20)18-10-5-6-11(12(7-10)22-4)13-8-17-9-23-13/h5-9H,1-4H3,(H,18,20)(H,19,21)	PDB MMDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Roche Discovery Welwyn Curated by ChEMBL					Assay Description Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenase				Bioorg Med Chem Lett 13: 1691-4 (2003) BindingDB Entry DOI: 10.7270/Q21N83B7
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50112565 (CHEMBL25138 | N-tert-Butyl-N'-(3-methoxy-4-oxazol-...) Show SMILES COc1cc(NC(=O)C(=O)NC(C)(C)C)ccc1-c1cnco1 Show InChI InChI=1S/C16H19N3O4/c1-16(2,3)19-15(21)14(20)18-10-5-6-11(12(7-10)22-4)13-8-17-9-23-13/h5-9H,1-4H3,(H,18,20)(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of inosine-5'-monophosphate dehydrogenase 2.				Bioorg Med Chem Lett 13: 2059-63 (2003) BindingDB Entry DOI: 10.7270/Q22Z14X1
					More data for this Ligand-Target Pair