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SMILES: CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(c(Cl)c2)-c2ccccc2Cl)cc1

InChI Key: InChIKey=DBYNLFRSPSIIBZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50112601   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))		BDBM50112601
PNG
(CHEMBL3609391)
Show SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(c(Cl)c2)-c2ccccc2Cl)cc1
Show InChI InChI=1S/C22H19Cl2NO3S/c1-2-29(27,28)17-10-7-15(8-11-17)13-22(26)25-16-9-12-19(21(24)14-16)18-5-3-4-6-20(18)23/h3-12,14H,2,13H2,1H3,(H,25,26)
PDB

UniProtKB/SwissProt

antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 5n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of RORgammat (unknown origin) assessed as inhibition of agonist-induced response by FRET assay

ACS Med Chem Lett 6: 787-92 (2015)


BindingDB Entry DOI: 10.7270/Q2XG9SWD
More data for this
Ligand-Target Pair