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BDBM50112775 (+/-) Propane-2-sulfonic acid [2-(4-chloro-phenyl)-cyclopentyl]-amide::CHEMBL63816

SMILES: CC(C)S(=O)(=O)N[C@@H]1CCC[C@@H]1c1ccc(Cl)cc1

InChI Key: InChIKey=HWBOIASHMSQVLM-ZIAGYGMSSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50112775   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate receptor ionotropic AMPA


(Homo sapiens (Human))
BDBM50112775
PNG
((+/-) Propane-2-sulfonic acid [2-(4-chloro-phenyl)...)
Show SMILES CC(C)S(=O)(=O)N[C@@H]1CCC[C@@H]1c1ccc(Cl)cc1
Show InChI InChI=1S/C14H20ClNO2S/c1-10(2)19(17,18)16-14-5-3-4-13(14)11-6-8-12(15)9-7-11/h6-10,13-14,16H,3-5H2,1-2H3/t13-,14-/m1/s1
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MMDB

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PubMed
n/an/an/an/a 247n/an/an/an/a



NPS Allelix Corporation

Curated by ChEMBL


Assay Description
Potentiation of responses mediated by 100 uM L-glutamate in transfected HEK293 cells expressing human homomeric iGluR4 flip receptors.


J Med Chem 45: 2101-11 (2002)


BindingDB Entry DOI: 10.7270/Q20R9NRB
More data for this
Ligand-Target Pair