BDBM50112775 (+/-) Propane-2-sulfonic acid [2-(4-chloro-phenyl)-cyclopentyl]-amide::CHEMBL63816
SMILES: CC(C)S(=O)(=O)N[C@@H]1CCC[C@@H]1c1ccc(Cl)cc1
InChI Key: InChIKey=HWBOIASHMSQVLM-ZIAGYGMSSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor ionotropic AMPA (Homo sapiens (Human)) | BDBM50112775 ((+/-) Propane-2-sulfonic acid [2-(4-chloro-phenyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 247 | n/a | n/a | n/a | n/a |
NPS Allelix Corporation Curated by ChEMBL | Assay Description Potentiation of responses mediated by 100 uM L-glutamate in transfected HEK293 cells expressing human homomeric iGluR4 flip receptors. | J Med Chem 45: 2101-11 (2002) BindingDB Entry DOI: 10.7270/Q20R9NRB | |||||||||||
More data for this Ligand-Target Pair |