BDBM50112900 CHEMBL3600843

SMILES: CCCC[C@@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)N(C)C(=O)[C@@H](Cc2ccc3ccccc3c2)N(C)C(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O

InChI Key: InChIKey=PIVHBXZYYYPXHW-PRXASQLMSA-N

Data: 4 IC50  4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50112900   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM50112900 (CHEMBL3600843) Show SMILES CCCC[C@@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)N(C)C(=O)[C@@H](Cc2ccc3ccccc3c2)N(C)C(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O |r| Show InChI InChI=1S/C56H75N15O9/c1-5-6-17-42(65-33(2)72)50(75)67-44-29-48(73)61-23-12-11-19-41(49(57)74)66-51(76)43(27-37-30-63-40-18-10-9-16-39(37)40)68-53(78)46(20-13-24-62-56(58)59)70(3)55(80)47(26-34-21-22-35-14-7-8-15-36(35)25-34)71(4)54(79)45(69-52(44)77)28-38-31-60-32-64-38/h7-10,14-16,18,21-22,25,30-32,41-47,63H,5-6,11-13,17,19-20,23-24,26-29H2,1-4H3,(H2,57,74)(H,60,64)(H,61,73)(H,65,72)(H,66,76)(H,67,75)(H,68,78)(H,69,77)(H4,58,59,62)/t41-,42+,43-,44-,45-,46-,47+/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Displacement of [125I]-[Nle4,D-Phe7]-alpha-MSH from human MC1 receptor expressed in HEK293 cells after 40 mins by luminescence counting				J Med Chem 58: 6359-67 (2015) BindingDB Entry DOI: 10.7270/Q251410F
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM50112900 (CHEMBL3600843) Show SMILES CCCC[C@@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)N(C)C(=O)[C@@H](Cc2ccc3ccccc3c2)N(C)C(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O |r| Show InChI InChI=1S/C56H75N15O9/c1-5-6-17-42(65-33(2)72)50(75)67-44-29-48(73)61-23-12-11-19-41(49(57)74)66-51(76)43(27-37-30-63-40-18-10-9-16-39(37)40)68-53(78)46(20-13-24-62-56(58)59)70(3)55(80)47(26-34-21-22-35-14-7-8-15-36(35)25-34)71(4)54(79)45(69-52(44)77)28-38-31-60-32-64-38/h7-10,14-16,18,21-22,25,30-32,41-47,63H,5-6,11-13,17,19-20,23-24,26-29H2,1-4H3,(H2,57,74)(H,60,64)(H,61,73)(H,65,72)(H,66,76)(H,67,75)(H,68,78)(H,69,77)(H4,58,59,62)/t41-,42+,43-,44-,45-,46-,47+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Agonist activity at human MC3 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulation using [3H]-cAMP by luminescence counting				J Med Chem 58: 6359-67 (2015) BindingDB Entry DOI: 10.7270/Q251410F
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50112900 (CHEMBL3600843) Show SMILES CCCC[C@@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)N(C)C(=O)[C@@H](Cc2ccc3ccccc3c2)N(C)C(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O |r| Show InChI InChI=1S/C56H75N15O9/c1-5-6-17-42(65-33(2)72)50(75)67-44-29-48(73)61-23-12-11-19-41(49(57)74)66-51(76)43(27-37-30-63-40-18-10-9-16-39(37)40)68-53(78)46(20-13-24-62-56(58)59)70(3)55(80)47(26-34-21-22-35-14-7-8-15-36(35)25-34)71(4)54(79)45(69-52(44)77)28-38-31-60-32-64-38/h7-10,14-16,18,21-22,25,30-32,41-47,63H,5-6,11-13,17,19-20,23-24,26-29H2,1-4H3,(H2,57,74)(H,60,64)(H,61,73)(H,65,72)(H,66,76)(H,67,75)(H,68,78)(H,69,77)(H4,58,59,62)/t41-,42+,43-,44-,45-,46-,47+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	36	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Agonist activity at human MC4 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulation using [3H]-cAMP by luminescence counting				J Med Chem 58: 6359-67 (2015) BindingDB Entry DOI: 10.7270/Q251410F
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM50112900 (CHEMBL3600843) Show SMILES CCCC[C@@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)N(C)C(=O)[C@@H](Cc2ccc3ccccc3c2)N(C)C(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O |r| Show InChI InChI=1S/C56H75N15O9/c1-5-6-17-42(65-33(2)72)50(75)67-44-29-48(73)61-23-12-11-19-41(49(57)74)66-51(76)43(27-37-30-63-40-18-10-9-16-39(37)40)68-53(78)46(20-13-24-62-56(58)59)70(3)55(80)47(26-34-21-22-35-14-7-8-15-36(35)25-34)71(4)54(79)45(69-52(44)77)28-38-31-60-32-64-38/h7-10,14-16,18,21-22,25,30-32,41-47,63H,5-6,11-13,17,19-20,23-24,26-29H2,1-4H3,(H2,57,74)(H,60,64)(H,61,73)(H,65,72)(H,66,76)(H,67,75)(H,68,78)(H,69,77)(H4,58,59,62)/t41-,42+,43-,44-,45-,46-,47+/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	759	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Agonist activity at human MC1 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulation using [3H]-cAMP by luminescence counting				J Med Chem 58: 6359-67 (2015) BindingDB Entry DOI: 10.7270/Q251410F
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (MC5R) (Homo sapiens (Human))	BDBM50112900 (CHEMBL3600843) Show SMILES CCCC[C@@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)N(C)C(=O)[C@@H](Cc2ccc3ccccc3c2)N(C)C(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O |r| Show InChI InChI=1S/C56H75N15O9/c1-5-6-17-42(65-33(2)72)50(75)67-44-29-48(73)61-23-12-11-19-41(49(57)74)66-51(76)43(27-37-30-63-40-18-10-9-16-39(37)40)68-53(78)46(20-13-24-62-56(58)59)70(3)55(80)47(26-34-21-22-35-14-7-8-15-36(35)25-34)71(4)54(79)45(69-52(44)77)28-38-31-60-32-64-38/h7-10,14-16,18,21-22,25,30-32,41-47,63H,5-6,11-13,17,19-20,23-24,26-29H2,1-4H3,(H2,57,74)(H,60,64)(H,61,73)(H,65,72)(H,66,76)(H,67,75)(H,68,78)(H,69,77)(H4,58,59,62)/t41-,42+,43-,44-,45-,46-,47+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Displacement of [125I]-[Nle4,D-Phe7]-alpha-MSH from human MC5 receptor expressed in HEK293 cells after 40 mins by luminescence counting				J Med Chem 58: 6359-67 (2015) BindingDB Entry DOI: 10.7270/Q251410F
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM50112900 (CHEMBL3600843) Show SMILES CCCC[C@@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)N(C)C(=O)[C@@H](Cc2ccc3ccccc3c2)N(C)C(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O |r| Show InChI InChI=1S/C56H75N15O9/c1-5-6-17-42(65-33(2)72)50(75)67-44-29-48(73)61-23-12-11-19-41(49(57)74)66-51(76)43(27-37-30-63-40-18-10-9-16-39(37)40)68-53(78)46(20-13-24-62-56(58)59)70(3)55(80)47(26-34-21-22-35-14-7-8-15-36(35)25-34)71(4)54(79)45(69-52(44)77)28-38-31-60-32-64-38/h7-10,14-16,18,21-22,25,30-32,41-47,63H,5-6,11-13,17,19-20,23-24,26-29H2,1-4H3,(H2,57,74)(H,60,64)(H,61,73)(H,65,72)(H,66,76)(H,67,75)(H,68,78)(H,69,77)(H4,58,59,62)/t41-,42+,43-,44-,45-,46-,47+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Displacement of [125I]-[Nle4,D-Phe7]-alpha-MSH from human MC3 receptor expressed in HEK293 cells after 40 mins by luminescence counting				J Med Chem 58: 6359-67 (2015) BindingDB Entry DOI: 10.7270/Q251410F
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50112900 (CHEMBL3600843) Show SMILES CCCC[C@@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)N(C)C(=O)[C@@H](Cc2ccc3ccccc3c2)N(C)C(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O |r| Show InChI InChI=1S/C56H75N15O9/c1-5-6-17-42(65-33(2)72)50(75)67-44-29-48(73)61-23-12-11-19-41(49(57)74)66-51(76)43(27-37-30-63-40-18-10-9-16-39(37)40)68-53(78)46(20-13-24-62-56(58)59)70(3)55(80)47(26-34-21-22-35-14-7-8-15-36(35)25-34)71(4)54(79)45(69-52(44)77)28-38-31-60-32-64-38/h7-10,14-16,18,21-22,25,30-32,41-47,63H,5-6,11-13,17,19-20,23-24,26-29H2,1-4H3,(H2,57,74)(H,60,64)(H,61,73)(H,65,72)(H,66,76)(H,67,75)(H,68,78)(H,69,77)(H4,58,59,62)/t41-,42+,43-,44-,45-,46-,47+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	507	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Displacement of [125I]-[Nle4,D-Phe7]-alpha-MSH from human MC4 receptor expressed in HEK293 cells after 40 mins by luminescence counting				J Med Chem 58: 6359-67 (2015) BindingDB Entry DOI: 10.7270/Q251410F
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (MC5R) (Homo sapiens (Human))	BDBM50112900 (CHEMBL3600843) Show SMILES CCCC[C@@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)N(C)C(=O)[C@@H](Cc2ccc3ccccc3c2)N(C)C(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O |r| Show InChI InChI=1S/C56H75N15O9/c1-5-6-17-42(65-33(2)72)50(75)67-44-29-48(73)61-23-12-11-19-41(49(57)74)66-51(76)43(27-37-30-63-40-18-10-9-16-39(37)40)68-53(78)46(20-13-24-62-56(58)59)70(3)55(80)47(26-34-21-22-35-14-7-8-15-36(35)25-34)71(4)54(79)45(69-52(44)77)28-38-31-60-32-64-38/h7-10,14-16,18,21-22,25,30-32,41-47,63H,5-6,11-13,17,19-20,23-24,26-29H2,1-4H3,(H2,57,74)(H,60,64)(H,61,73)(H,65,72)(H,66,76)(H,67,75)(H,68,78)(H,69,77)(H4,58,59,62)/t41-,42+,43-,44-,45-,46-,47+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Agonist activity at human MC5 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulation using [3H]-cAMP by luminescence counting				J Med Chem 58: 6359-67 (2015) BindingDB Entry DOI: 10.7270/Q251410F
					More data for this Ligand-Target Pair