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SMILES: NC(=O)c1cccc2CN(C3CCN(CC3)C(=O)C3CC3)C(=O)c12

InChI Key: InChIKey=VUYFNAULJNANJS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50113455   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50113455
PNG
(CHEMBL3605988)
Show SMILES NC(=O)c1cccc2CN(C3CCN(CC3)C(=O)C3CC3)C(=O)c12
Show InChI InChI=1S/C18H21N3O3/c19-16(22)14-3-1-2-12-10-21(18(24)15(12)14)13-6-8-20(9-7-13)17(23)11-4-5-11/h1-3,11,13H,4-10H2,(H2,19,22)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/a 150n/an/an/an/an/a



Nerviano Medical Sciences Srl

Curated by ChEMBL


Assay Description
Binding affinity to full length recombinant human PARP-1 by fluorescence polarization displacement assay

J Med Chem 58: 6875-98 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00680
BindingDB Entry DOI: 10.7270/Q2JD4ZKF
More data for this
Ligand-Target Pair