BDBM50113597 (E)-3-(3-Carbamimidoyl-phenyl)-2-methyl-N-(2'-sulfamoyl-biphenyl-4-yl)-acrylamide::CHEMBL285725

SMILES: C\C(=C\c1cccc(c1)C(N)=N)C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O

InChI Key: InChIKey=OCRXUQYDFYVVMJ-SQFISAMPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50113597   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50113597 ((E)-3-(3-Carbamimidoyl-phenyl)-2-methyl-N-(2'-sulf...) Show SMILES C\C(=C\c1cccc(c1)C(N)=N)C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O Show InChI InChI=1S/C23H22N4O3S/c1-15(13-16-5-4-6-18(14-16)22(24)25)23(28)27-19-11-9-17(10-12-19)20-7-2-3-8-21(20)31(26,29)30/h2-14H,1H3,(H3,24,25)(H,27,28)(H2,26,29,30)/b15-13-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	362	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against factor Xa				Bioorg Med Chem Lett 12: 1511-5 (2002) BindingDB Entry DOI: 10.7270/Q2P84B6X
					More data for this Ligand-Target Pair