BDBM50113602 (E)-3-(3-Carbamimidoyl-phenyl)-N-(2'-sulfamoyl-biphenyl-4-yl)-acrylamide::CHEMBL290382

SMILES: NC(=N)c1cccc(\C=C/C(=O)Nc2ccc(cc2)-c2ccccc2S(N)(=O)=O)c1

InChI Key: InChIKey=JKDFPVVULZXZIM-JYRVWZFOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50113602   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50113602 ((E)-3-(3-Carbamimidoyl-phenyl)-N-(2'-sulfamoyl-bip...) Show SMILES NC(=N)c1cccc(\C=C/C(=O)Nc2ccc(cc2)-c2ccccc2S(N)(=O)=O)c1 Show InChI InChI=1S/C22H20N4O3S/c23-22(24)17-5-3-4-15(14-17)8-13-21(27)26-18-11-9-16(10-12-18)19-6-1-2-7-20(19)30(25,28)29/h1-14H,(H3,23,24)(H,26,27)(H2,25,28,29)/b13-8-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against factor Xa				Bioorg Med Chem Lett 12: 1511-5 (2002) BindingDB Entry DOI: 10.7270/Q2P84B6X
					More data for this Ligand-Target Pair