null

SMILES: COc1ccc(NCCNC(=O)[C@H](CC(C)C)NC(=O)c2ncn(n2)-c2ccccc2Cl)cc1

InChI Key: InChIKey=OXSJNGDTLSLRIV-FQEVSTJZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50113669   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Procathepsin L (Homo sapiens (Human))	BDBM50113669 (1-(2-Chloro-phenyl)-1H-[1,2,4]triazole-3-carboxyli...) Show SMILES COc1ccc(NCCNC(=O)[C@H](CC(C)C)NC(=O)c2ncn(n2)-c2ccccc2Cl)cc1 Show InChI InChI=1S/C24H29ClN6O3/c1-16(2)14-20(23(32)27-13-12-26-17-8-10-18(34-3)11-9-17)29-24(33)22-28-15-31(30-22)21-7-5-4-6-19(21)25/h4-11,15-16,20,26H,12-14H2,1-3H3,(H,27,32)(H,29,33)/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of recombinant human cathepsin L in a fluorescence assay.				J Med Chem 45: 2352-4 (2002) BindingDB Entry DOI: 10.7270/Q2DV1J73
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM50113669 (1-(2-Chloro-phenyl)-1H-[1,2,4]triazole-3-carboxyli...) Show SMILES COc1ccc(NCCNC(=O)[C@H](CC(C)C)NC(=O)c2ncn(n2)-c2ccccc2Cl)cc1 Show InChI InChI=1S/C24H29ClN6O3/c1-16(2)14-20(23(32)27-13-12-26-17-8-10-18(34-3)11-9-17)29-24(33)22-28-15-31(30-22)21-7-5-4-6-19(21)25/h4-11,15-16,20,26H,12-14H2,1-3H3,(H,27,32)(H,29,33)/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of recombinant human cathepsin S in a fluorescence assay				J Med Chem 45: 2352-4 (2002) BindingDB Entry DOI: 10.7270/Q2DV1J73
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50113669 (1-(2-Chloro-phenyl)-1H-[1,2,4]triazole-3-carboxyli...) Show SMILES COc1ccc(NCCNC(=O)[C@H](CC(C)C)NC(=O)c2ncn(n2)-c2ccccc2Cl)cc1 Show InChI InChI=1S/C24H29ClN6O3/c1-16(2)14-20(23(32)27-13-12-26-17-8-10-18(34-3)11-9-17)29-24(33)22-28-15-31(30-22)21-7-5-4-6-19(21)25/h4-11,15-16,20,26H,12-14H2,1-3H3,(H,27,32)(H,29,33)/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of recombinant human cathepsin K in fluorescence assay				J Med Chem 45: 2352-4 (2002) BindingDB Entry DOI: 10.7270/Q2DV1J73
					More data for this Ligand-Target Pair