BDBM50113804 4-Anthracen-9-ylmethyl-5-piperidin-4-yl-isoxazol-3-ol; hydrobromide::CHEMBL543125
SMILES: O=c1[nH]oc(C2CCNCC2)c1Cc1c2ccccc2cc2ccccc12
InChI Key: InChIKey=NUSNKEBTPCBSNA-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gamma-aminobutyric acid type B receptor subunit 1 (Rattus norvegicus (Rat)) | BDBM50113804 (4-Anthracen-9-ylmethyl-5-piperidin-4-yl-isoxazol-3...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomes | J Med Chem 45: 2454-68 (2002) BindingDB Entry DOI: 10.7270/Q2D21Z91 | |||||||||||
More data for this Ligand-Target Pair |