BDBM50114233 1-[4-(4-Butoxy-phenylsulfanyl)-phenyl]-3-(5-tert-butyl-2-methyl-2H-pyrazol-3-yl)-urea::CHEMBL38548

SMILES: CCCCOc1ccc(Sc2ccc(NC(=O)Nc3cc(nn3C)C(C)(C)C)cc2)cc1

InChI Key: InChIKey=XXYYIYBSOIFUIG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50114233   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50114233 (1-[4-(4-Butoxy-phenylsulfanyl)-phenyl]-3-(5-tert-b...) Show SMILES CCCCOc1ccc(Sc2ccc(NC(=O)Nc3cc(nn3C)C(C)(C)C)cc2)cc1 Show InChI InChI=1S/C25H32N4O2S/c1-6-7-16-31-19-10-14-21(15-11-19)32-20-12-8-18(9-13-20)26-24(30)27-23-17-22(25(2,3)4)28-29(23)5/h8-15,17H,6-7,16H2,1-5H3,(H2,26,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2				Bioorg Med Chem Lett 12: 1559-62 (2002) BindingDB Entry DOI: 10.7270/Q2CV4H28
					More data for this Ligand-Target Pair