BDBM50114243 CHEMBL289155::N-(4-{4-[3-(5-tert-Butyl-2-methyl-2H-pyrazol-3-yl)-ureido]-phenoxy}-phenyl)-acetamide

SMILES: CC(=O)Nc1ccc(Oc2ccc(NC(=O)Nc3cc(nn3C)C(C)(C)C)cc2)cc1

InChI Key: InChIKey=QTJDAXPHEZBXPA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50114243   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50114243 (CHEMBL289155 | N-(4-{4-[3-(5-tert-Butyl-2-methyl-2...) Show SMILES CC(=O)Nc1ccc(Oc2ccc(NC(=O)Nc3cc(nn3C)C(C)(C)C)cc2)cc1 Show InChI InChI=1S/C23H27N5O3/c1-15(29)24-16-6-10-18(11-7-16)31-19-12-8-17(9-13-19)25-22(30)26-21-14-20(23(2,3)4)27-28(21)5/h6-14H,1-5H3,(H,24,29)(H2,25,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	235	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2				Bioorg Med Chem Lett 12: 1559-62 (2002) BindingDB Entry DOI: 10.7270/Q2CV4H28
					More data for this Ligand-Target Pair