BDBM50114460 4-(3-Carbamimidoyl-phenoxy)-3-[(2'-sulfamoyl-biphenyl-4-carbonyl)-amino]-benzoic acid::CHEMBL295128

SMILES: NC(=N)c1cccc(Oc2ccc(cc2NC(=O)c2ccc(cc2)-c2ccccc2S(N)(=O)=O)C(O)=O)c1

InChI Key: InChIKey=KWPUGQUTZXLRNF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50114460   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50114460 (4-(3-Carbamimidoyl-phenoxy)-3-[(2'-sulfamoyl-biphe...) Show SMILES NC(=N)c1cccc(Oc2ccc(cc2NC(=O)c2ccc(cc2)-c2ccccc2S(N)(=O)=O)C(O)=O)c1 Show InChI InChI=1S/C27H22N4O6S/c28-25(29)18-4-3-5-20(14-18)37-23-13-12-19(27(33)34)15-22(23)31-26(32)17-10-8-16(9-11-17)21-6-1-2-7-24(21)38(30,35)36/h1-15H,(H3,28,29)(H,31,32)(H,33,34)(H2,30,35,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Tested in vitro for the inhibitory activity against Coagulation factor Xa				Bioorg Med Chem Lett 12: 1657-61 (2002) BindingDB Entry DOI: 10.7270/Q2R49Q2T
					More data for this Ligand-Target Pair