BDBM50114482 2'-Sulfamoyl-biphenyl-4-carboxylic acid [2-(3-carbamimidoyl-phenoxy)-ethyl]-methyl-amide::CHEMBL43039

SMILES: CN(CCOc1cccc(c1)C(N)=N)C(=O)c1ccc(cc1)-c1ccccc1S(N)(=O)=O

InChI Key: InChIKey=QNFFIKJKLRYKMI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50114482   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50114482 (2'-Sulfamoyl-biphenyl-4-carboxylic acid [2-(3-carb...) Show SMILES CN(CCOc1cccc(c1)C(N)=N)C(=O)c1ccc(cc1)-c1ccccc1S(N)(=O)=O Show InChI InChI=1S/C23H24N4O4S/c1-27(13-14-31-19-6-4-5-18(15-19)22(24)25)23(28)17-11-9-16(10-12-17)20-7-2-3-8-21(20)32(26,29)30/h2-12,15H,13-14H2,1H3,(H3,24,25)(H2,26,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Tested in vitro for the inhibitory activity against Coagulation factor Xa				Bioorg Med Chem Lett 12: 1657-61 (2002) BindingDB Entry DOI: 10.7270/Q2R49Q2T
					More data for this Ligand-Target Pair