BDBM50114663 CHEMBL3609655

SMILES: [H][C@@]12C[C@@H](CCN1C(=O)c1cccc(NC(=O)Nc3cnccn3)c21)OC

InChI Key: InChIKey=VRSPGAKIMFTTJM-RISCZKNCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50114663   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual-specificity tyrosine-phosphorylation regulated kinase 1A (Homo sapiens (Human))	BDBM50114663 (CHEMBL3609655) Show SMILES [H][C@@]12C[C@@H](CCN1C(=O)c1cccc(NC(=O)Nc3cnccn3)c21)OC |r| Show InChI InChI=1S/C18H19N5O3/c1-26-11-5-8-23-14(9-11)16-12(17(23)24)3-2-4-13(16)21-18(25)22-15-10-19-6-7-20-15/h2-4,6-7,10-11,14H,5,8-9H2,1H3,(H2,20,21,22,25)/t11-,14+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 7311 Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged DYRK1A expressed in Escherichia coli				Eur J Med Chem 101: 274-87 (2015) BindingDB Entry DOI: 10.7270/Q24T6M53
					More data for this Ligand-Target Pair