null

SMILES: NC(=S)NN=Cc1cccc(Br)c1

InChI Key: InChIKey=FGGWIXJNLRDBPW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50114665   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM50114665 (2-(trifluoromethyl)benzaldehyde thiosemicarbazone ...) Show SMILES NC(=S)NN=Cc1cccc(Br)c1 |w:5.5| Show InChI InChI=1S/C8H8BrN3S/c9-7-3-1-2-6(4-7)5-11-12-8(10)13/h1-5H,(H3,10,12,13)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COMSATS Institute of Information Technology Curated by ChEMBL					Assay Description Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol method				Eur J Med Chem 46: 5473-9 (2011) Article DOI: 10.1016/j.ejmech.2011.09.009 BindingDB Entry DOI: 10.7270/Q2GM87QH
					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50114665 (2-(trifluoromethyl)benzaldehyde thiosemicarbazone ...) Show SMILES NC(=S)NN=Cc1cccc(Br)c1 |w:5.5| Show InChI InChI=1S/C8H8BrN3S/c9-7-3-1-2-6(4-7)5-11-12-8(10)13/h1-5H,(H3,10,12,13)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California-San Francisco Curated by ChEMBL					Assay Description Inhibitory activity against Trypanosoma cruzi cathepsin L-like protease (cruzain) was determined using purified recombinant protein				J Med Chem 45: 2695-707 (2002) BindingDB Entry DOI: 10.7270/Q2ZP45FM
					More data for this Ligand-Target Pair
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM50114665 (2-(trifluoromethyl)benzaldehyde thiosemicarbazone ...) Show SMILES NC(=S)NN=Cc1cccc(Br)c1 |w:5.5| Show InChI InChI=1S/C8H8BrN3S/c9-7-3-1-2-6(4-7)5-11-12-8(10)13/h1-5H,(H3,10,12,13)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	767	n/a	n/a	n/a	n/a	n/a	n/a
COMSATS Institute of Information Technology Curated by ChEMBL					Assay Description Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol method				Eur J Med Chem 46: 5473-9 (2011) Article DOI: 10.1016/j.ejmech.2011.09.009 BindingDB Entry DOI: 10.7270/Q2GM87QH
					More data for this Ligand-Target Pair