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SMILES: Cc1cc(ccc1Cl)-c1csc(=N)n1-c1ccc(Cl)cc1

InChI Key: InChIKey=WWICDNHPMVBSRN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50114997   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50114997 (4-(4-Chloro-3-methyl-phenyl)-3-(4-chloro-phenyl)-3...) Show SMILES Cc1cc(ccc1Cl)-c1csc(=N)n1-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H12Cl2N2S/c1-10-8-11(2-7-14(10)18)15-9-21-16(19)20(15)13-5-3-12(17)4-6-13/h2-9,19H,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Tested for the ability to displace [3H]WIN-35 428 binding to dopamine transporter (DAT) in rat striatal tissue				Bioorg Med Chem Lett 12: 1775-8 (2002) BindingDB Entry DOI: 10.7270/Q2Z038Q5
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50114997 (4-(4-Chloro-3-methyl-phenyl)-3-(4-chloro-phenyl)-3...) Show SMILES Cc1cc(ccc1Cl)-c1csc(=N)n1-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H12Cl2N2S/c1-10-8-11(2-7-14(10)18)15-9-21-16(19)20(15)13-5-3-12(17)4-6-13/h2-9,19H,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Tested for the ability to displace [3H]WIN-35 428 binding to dopamine transporter (DAT) in rat striatal tissue				Bioorg Med Chem Lett 12: 1775-8 (2002) BindingDB Entry DOI: 10.7270/Q2Z038Q5
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50114997 (4-(4-Chloro-3-methyl-phenyl)-3-(4-chloro-phenyl)-3...) Show SMILES Cc1cc(ccc1Cl)-c1csc(=N)n1-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H12Cl2N2S/c1-10-8-11(2-7-14(10)18)15-9-21-16(19)20(15)13-5-3-12(17)4-6-13/h2-9,19H,1H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	99	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Compound was tested for the inhibition of norepinephrine [3H]NE reuptake into rat cortical membranes				Bioorg Med Chem Lett 12: 1775-8 (2002) BindingDB Entry DOI: 10.7270/Q2Z038Q5
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50114997 (4-(4-Chloro-3-methyl-phenyl)-3-(4-chloro-phenyl)-3...) Show SMILES Cc1cc(ccc1Cl)-c1csc(=N)n1-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H12Cl2N2S/c1-10-8-11(2-7-14(10)18)15-9-21-16(19)20(15)13-5-3-12(17)4-6-13/h2-9,19H,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	225	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Compound was tested for the inhibition of serotonin [3H]SER reuptake into rat forebrain membranes				Bioorg Med Chem Lett 12: 1775-8 (2002) BindingDB Entry DOI: 10.7270/Q2Z038Q5
					More data for this Ligand-Target Pair