BDBM50115200 CHEMBL3608545
SMILES: Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)c4cn(nc4-c4ccccc4)-c4ccccc4)cc3F)c2s1
InChI Key: InChIKey=ZBSTZJARMUEZIU-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50115200 (CHEMBL3608545) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires ChemRF Inc./ChemRF Laboratories Inc. Curated by ChEMBL | Assay Description Inhibition of c-Met phosphorylation in human MKN45 cells | Bioorg Med Chem Lett 25: 3810-5 (2015) BindingDB Entry DOI: 10.7270/Q2028T99 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage-stimulating protein receptor (Homo sapiens (Human)) | BDBM50115200 (CHEMBL3608545) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires ChemRF Inc./ChemRF Laboratories Inc. Curated by ChEMBL | Assay Description Inhibition of human RON | Bioorg Med Chem Lett 25: 3810-5 (2015) BindingDB Entry DOI: 10.7270/Q2028T99 | |||||||||||
More data for this Ligand-Target Pair |