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SMILES: [#6]-c1ccnc2-[#6]-[#6](-[#6]-[#6](=[#7]\[#7]=[#6](\[#7])-[#7])-c12)-c1ccccc1

InChI Key: InChIKey=NYCXPFMRNFIPAQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50115261   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/hydrogen exchanger 1


(Rattus norvegicus)		BDBM50115261
PNG
(CHEMBL543865 | N-(4-methyl-7-phenyl-5,6,7,8-tetrah...)
Show SMILES [#6]-c1ccnc2-[#6]-[#6](-[#6]-[#6](=[#7]\[#7]=[#6](\[#7])-[#7])-c12)-c1ccccc1 |w:10.10|
Show InChI InChI=1S/C17H19N5/c1-11-7-8-20-14-9-13(12-5-3-2-4-6-12)10-15(16(11)14)21-22-17(18)19/h2-8,13H,9-10H2,1H3,(H4,18,19,22)
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n/an/a 91n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibition

J Med Chem 45: 3009-21 (2002)


BindingDB Entry DOI: 10.7270/Q2V40VZN
More data for this
Ligand-Target Pair