BDBM50115574 4-(3-Benzoylamino-phenyl)-2-hydroxy-4-oxo-but-2-enoic acid::CHEMBL322472::CHEMBL366966

SMILES: OC(=O)C(=O)CC(=O)c1cccc(NC(=O)c2ccccc2)c1

InChI Key: InChIKey=SZGGDEQGRQUBNR-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50115574   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50115574 (4-(3-Benzoylamino-phenyl)-2-hydroxy-4-oxo-but-2-en...) Show SMILES OC(=O)C(=O)CC(=O)c1cccc(NC(=O)c2ccccc2)c1 Show InChI InChI=1S/C17H13NO5/c19-14(10-15(20)17(22)23)12-7-4-8-13(9-12)18-16(21)11-5-2-1-3-6-11/h1-9H,10H2,(H,18,21)(H,22,23)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Italy. Vinc Curated by ChEMBL					Assay Description Inhibitory activity against Hepatitis C virus RNA dependent RNA polymerase nonstructural protein 5B				J Med Chem 47: 14-7 (2003) Article DOI: 10.1021/jm0342109 BindingDB Entry DOI: 10.7270/Q2736QB8
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50115574 (4-(3-Benzoylamino-phenyl)-2-hydroxy-4-oxo-but-2-en...) Show SMILES OC(=O)C(=O)CC(=O)c1cccc(NC(=O)c2ccccc2)c1 Show InChI InChI=1S/C17H13NO5/c19-14(10-15(20)17(22)23)12-7-4-8-13(9-12)18-16(21)11-5-2-1-3-6-11/h1-9H,10H2,(H,18,21)(H,22,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute/NIH Curated by ChEMBL					Assay Description Inhibitory effect on 3'-processing(3'-P) of proviral DNA in an extracellular HIV-1 integrase assay				J Med Chem 45: 3184-94 (2002) BindingDB Entry DOI: 10.7270/Q26D5TPD
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50115574 (4-(3-Benzoylamino-phenyl)-2-hydroxy-4-oxo-but-2-en...) Show SMILES OC(=O)C(=O)CC(=O)c1cccc(NC(=O)c2ccccc2)c1 Show InChI InChI=1S/C17H13NO5/c19-14(10-15(20)17(22)23)12-7-4-8-13(9-12)18-16(21)11-5-2-1-3-6-11/h1-9H,10H2,(H,18,21)(H,22,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute/NIH Curated by ChEMBL					Assay Description Inhibitory effect on strand transfer of proviral DNA into host DNA in an extracellular HIV-1 integrase assay				J Med Chem 45: 3184-94 (2002) BindingDB Entry DOI: 10.7270/Q26D5TPD
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50115574 (4-(3-Benzoylamino-phenyl)-2-hydroxy-4-oxo-but-2-en...) Show SMILES OC(=O)C(=O)CC(=O)c1cccc(NC(=O)c2ccccc2)c1 Show InChI InChI=1S/C17H13NO5/c19-14(10-15(20)17(22)23)12-7-4-8-13(9-12)18-16(21)11-5-2-1-3-6-11/h1-9H,10H2,(H,18,21)(H,22,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description Strand transfer inhibitory activity against HIV-1 integrase				J Med Chem 48: 7084-8 (2005) Article DOI: 10.1021/jm050549e BindingDB Entry DOI: 10.7270/Q27W6BR1
					More data for this Ligand-Target Pair