BDBM50115661 CHEMBL320497::N,8-dihydroxy-8-(hydroxyamino)octanamide::N1,N8-dihydroxyoctanediamide::Octanedioic acid bis-hydroxyamide::Suberohydroxamic acid::Suberoic bis hydroxamic acid::Suberoyl bis hydroxamic acid

SMILES: ONC(=O)CCCCCCC(=O)NO

InChI Key: InChIKey=IDQPVOFTURLJPT-UHFFFAOYSA-N

Data: 5 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50115661   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase HD2 (Zea mays)	BDBM50115661 (CHEMBL320497 | N,8-dihydroxy-8-(hydroxyamino)octan...) Show SMILES ONC(=O)CCCCCCC(=O)NO Show InChI InChI=1S/C8H16N2O4/c11-7(9-13)5-3-1-2-4-6-8(12)10-14/h13-14H,1-6H2,(H,9,11)(H,10,12)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Westfälische Wilhelms-Universität Münster Curated by ChEMBL					Assay Description Inhibition of in vitro enzyme activity measured in a highly purified maize Histone deacetylase 2 preparation				J Med Chem 45: 3296-309 (2002) BindingDB Entry DOI: 10.7270/Q247497N
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 1 (Homo sapiens (Human))	BDBM50115661 (CHEMBL320497 | N,8-dihydroxy-8-(hydroxyamino)octan...) Show SMILES ONC(=O)CCCCCCC(=O)NO Show InChI InChI=1S/C8H16N2O4/c11-7(9-13)5-3-1-2-4-6-8(12)10-14/h13-14H,1-6H2,(H,9,11)(H,10,12)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC1 (unknown origin) by fluorimetric assay				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50115661 (CHEMBL320497 | N,8-dihydroxy-8-(hydroxyamino)octan...) Show SMILES ONC(=O)CCCCCCC(=O)NO Show InChI InChI=1S/C8H16N2O4/c11-7(9-13)5-3-1-2-4-6-8(12)10-14/h13-14H,1-6H2,(H,9,11)(H,10,12)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC6 in human HeLa cells assessed as inhibition of tubulin deacetylation incubated for overnight by cELISA				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50115661 (CHEMBL320497 | N,8-dihydroxy-8-(hydroxyamino)octan...) Show SMILES ONC(=O)CCCCCCC(=O)NO Show InChI InChI=1S/C8H16N2O4/c11-7(9-13)5-3-1-2-4-6-8(12)10-14/h13-14H,1-6H2,(H,9,11)(H,10,12)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) by fluorimetric assay				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50115661 (CHEMBL320497 | N,8-dihydroxy-8-(hydroxyamino)octan...) Show SMILES ONC(=O)CCCCCCC(=O)NO Show InChI InChI=1S/C8H16N2O4/c11-7(9-13)5-3-1-2-4-6-8(12)10-14/h13-14H,1-6H2,(H,9,11)(H,10,12)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC3 (unknown origin) by fluorimetric assay				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 2 (Homo sapiens (Human))	BDBM50115661 (CHEMBL320497 | N,8-dihydroxy-8-(hydroxyamino)octan...) Show SMILES ONC(=O)CCCCCCC(=O)NO Show InChI InChI=1S/C8H16N2O4/c11-7(9-13)5-3-1-2-4-6-8(12)10-14/h13-14H,1-6H2,(H,9,11)(H,10,12)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC2 (unknown origin) by fluorimetric assay				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
					More data for this Ligand-Target Pair