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SMILES: COc1ccc(\C=C\C(=O)c2ccccc2C(F)(F)F)c(OC)c1

InChI Key: InChIKey=NIBGUYJNZFITBL-CSKARUKUSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50115780   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nitric oxide synthase, inducible


(Mus musculus (mouse))		BDBM50115780
PNG
(3-(2,4-Dimethoxy-phenyl)-1-(2-trifluoromethyl-phen...)
Show SMILES COc1ccc(\C=C\C(=O)c2ccccc2C(F)(F)F)c(OC)c1
Show InChI InChI=1S/C18H15F3O3/c1-23-13-9-7-12(17(11-13)24-2)8-10-16(22)14-5-3-4-6-15(14)18(19,20)21/h3-11H,1-2H3/b10-8+
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Similars
PubMed
n/an/a 840n/an/an/an/an/an/a



Universidad de Valencia

Curated by ChEMBL


Assay Description
Inhibitory concentration of the compound required to produce 50% inhibition of the response was determined; range-0.461.81 uM

Bioorg Med Chem Lett 12: 1951-4 (2002)


BindingDB Entry DOI: 10.7270/Q2M61JKW
More data for this
Ligand-Target Pair