BDBM50116042 CHEMBL63861::{7-[3-(4-Benzyl-piperazin-1-ylmethyl)-pyrrol-1-yl]-6-nitro-2,3-dioxo-3,4-dihydro-2H-quinoxalin-1-yl}-acetic acid
SMILES: OC(=O)Cn1c2cc(c(cc2[nH]c(=O)c1=O)[N+]([O-])=O)-n1ccc(CN2CCN(Cc3ccccc3)CC2)c1
InChI Key: InChIKey=UWBHJOVXAJRYJM-UHFFFAOYSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
GRIK1 (Homo sapiens (Human)) | BDBM50116042 (CHEMBL63861 | {7-[3-(4-Benzyl-piperazin-1-ylmethyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott GmbH & Co. KG Curated by ChEMBL | Assay Description Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligand | Bioorg Med Chem Lett 12: 2113-6 (2002) BindingDB Entry DOI: 10.7270/Q22806XK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate-Kainate 7 (Homo sapiens (Human)) | BDBM50116042 (CHEMBL63861 | {7-[3-(4-Benzyl-piperazin-1-ylmethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 680 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott GmbH & Co. KG Curated by ChEMBL | Assay Description Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligand | Bioorg Med Chem Lett 12: 2113-6 (2002) BindingDB Entry DOI: 10.7270/Q22806XK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human)) | BDBM50116042 (CHEMBL63861 | {7-[3-(4-Benzyl-piperazin-1-ylmethyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott GmbH & Co. KG Curated by ChEMBL | Assay Description Binding affinity for human GluR6 expressed in HEK-293 cells using [3]H-kainate | Bioorg Med Chem Lett 12: 2113-6 (2002) BindingDB Entry DOI: 10.7270/Q22806XK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Grik5 (Homo sapiens (Human)) | BDBM50116042 (CHEMBL63861 | {7-[3-(4-Benzyl-piperazin-1-ylmethyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott GmbH & Co. KG Curated by ChEMBL | Assay Description Binding affinity towards cloned human Kai-2 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligand | Bioorg Med Chem Lett 12: 2113-6 (2002) BindingDB Entry DOI: 10.7270/Q22806XK | |||||||||||
More data for this Ligand-Target Pair |