BDBM50116132 (3-Methoxy-4-oxazol-5-yl-phenyl)-(4-methoxy-6-phenyl-[1,3,5]triazin-2-yl)-amine::CHEMBL68221

SMILES: COc1nc(Nc2ccc(-c3cnco3)c(OC)c2)nc(n1)-c1ccccc1

InChI Key: InChIKey=ASMVNNCXXGYFBC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50116132   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50116132 ((3-Methoxy-4-oxazol-5-yl-phenyl)-(4-methoxy-6-phen...) Show SMILES COc1nc(Nc2ccc(-c3cnco3)c(OC)c2)nc(n1)-c1ccccc1 Show InChI InChI=1S/C20H17N5O3/c1-26-16-10-14(8-9-15(16)17-11-21-12-28-17)22-19-23-18(24-20(25-19)27-2)13-6-4-3-5-7-13/h3-12H,1-2H3,(H,22,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)				Bioorg Med Chem Lett 12: 3125-8 (2002) BindingDB Entry DOI: 10.7270/Q2959GXF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50116132 ((3-Methoxy-4-oxazol-5-yl-phenyl)-(4-methoxy-6-phen...) Show SMILES COc1nc(Nc2ccc(-c3cnco3)c(OC)c2)nc(n1)-c1ccccc1 Show InChI InChI=1S/C20H17N5O3/c1-26-16-10-14(8-9-15(16)17-11-21-12-28-17)22-19-23-18(24-20(25-19)27-2)13-6-4-3-5-7-13/h3-12H,1-2H3,(H,22,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Inosine-5'-monophosphate dehydrogenase 2				Bioorg Med Chem Lett 12: 2137-40 (2002) BindingDB Entry DOI: 10.7270/Q2NZ86Z7
					More data for this Ligand-Target Pair