null

SMILES: CC(C)[C@H]1c2ccc(F)cc2[C@@H](C[C@@]1(CCN(C)CCCc1nc2ccccc2[nH]1)OC(=O)C(C)C)OCc1ccccc1

InChI Key: InChIKey=HCEKERAQUTWNGZ-QRWXSKHGSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50116568   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50116568 (CHEMBL3608941) Show SMILES CC(C)[C@H]1c2ccc(F)cc2[C@@H](C[C@@]1(CCN(C)CCCc1nc2ccccc2[nH]1)OC(=O)C(C)C)OCc1ccccc1 |r| Show InChI InChI=1S/C37H46FN3O3/c1-25(2)35-29-18-17-28(38)22-30(29)33(43-24-27-12-7-6-8-13-27)23-37(35,44-36(42)26(3)4)19-21-41(5)20-11-16-34-39-31-14-9-10-15-32(31)40-34/h6-10,12-15,17-18,22,25-26,33,35H,11,16,19-21,23-24H2,1-5H3,(H,39,40)/t33-,35+,37-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	132	n/a	n/a	n/a	n/a	n/a	n/a
Actelion Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant Cav3.2 channel (unknown origin) expressed in HEK293 cells assessed as effect on calcium flux incubated for 3 mins by FLIPR ...				Bioorg Med Chem Lett 25: 3941-6 (2015) BindingDB Entry DOI: 10.7270/Q24M96BF
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human))	BDBM50116568 (CHEMBL3608941) Show SMILES CC(C)[C@H]1c2ccc(F)cc2[C@@H](C[C@@]1(CCN(C)CCCc1nc2ccccc2[nH]1)OC(=O)C(C)C)OCc1ccccc1 |r| Show InChI InChI=1S/C37H46FN3O3/c1-25(2)35-29-18-17-28(38)22-30(29)33(43-24-27-12-7-6-8-13-27)23-37(35,44-36(42)26(3)4)19-21-41(5)20-11-16-34-39-31-14-9-10-15-32(31)40-34/h6-10,12-15,17-18,22,25-26,33,35H,11,16,19-21,23-24H2,1-5H3,(H,39,40)/t33-,35+,37-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	156	n/a	n/a	n/a	n/a	n/a	n/a
Actelion Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant Cav1.2 channel (unknown origin) expressed in HEK293 cells assessed as effect on calcium flux incubated for 3 mins by FLIPR ...				Bioorg Med Chem Lett 25: 3941-6 (2015) BindingDB Entry DOI: 10.7270/Q24M96BF
					More data for this Ligand-Target Pair