BDBM50116746 3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-[4-(2-oxo-3-pyridin-2-ylmethyl-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-pentyl}-N-ethyl-benzamide::CHEMBL311712

SMILES: CCN(C\C(=N/OC)[C@H](CCN1CCC(CC1)n1c2ccccc2n(Cc2ccccn2)c1=O)c1ccc(Cl)c(Cl)c1)C(=O)c1cc(Cl)cc(Cl)c1

InChI Key: InChIKey=RQVBYRWUISROIZ-FEWZWGNISA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50116746   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neurokinin 1 receptor (Homo sapiens (Human))	BDBM50116746 (3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)...) Show SMILES CCN(C\C(=N/OC)[C@H](CCN1CCC(CC1)n1c2ccccc2n(Cc2ccccn2)c1=O)c1ccc(Cl)c(Cl)c1)C(=O)c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C39H40Cl4N6O3/c1-3-47(38(50)27-20-28(40)23-29(41)21-27)25-35(45-52-2)32(26-11-12-33(42)34(43)22-26)15-19-46-17-13-31(14-18-46)49-37-10-5-4-9-36(37)48(39(49)51)24-30-8-6-7-16-44-30/h4-12,16,20-23,31-32H,3,13-15,17-19,24-25H2,1-2H3/b45-35+/t32-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity against recombinant human tachykinin receptor 1 in CHO cells using [3H]-Sar SP as radioligand				Bioorg Med Chem Lett 12: 2355-8 (2002) BindingDB Entry DOI: 10.7270/Q26T0KXW
					More data for this Ligand-Target Pair
Neurokinin 2 receptor (Homo sapiens (Human))	BDBM50116746 (3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)...) Show SMILES CCN(C\C(=N/OC)[C@H](CCN1CCC(CC1)n1c2ccccc2n(Cc2ccccn2)c1=O)c1ccc(Cl)c(Cl)c1)C(=O)c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C39H40Cl4N6O3/c1-3-47(38(50)27-20-28(40)23-29(41)21-27)25-35(45-52-2)32(26-11-12-33(42)34(43)22-26)15-19-46-17-13-31(14-18-46)49-37-10-5-4-9-36(37)48(39(49)51)24-30-8-6-7-16-44-30/h4-12,16,20-23,31-32H,3,13-15,17-19,24-25H2,1-2H3/b45-35+/t32-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity against recombinant human tachykinin receptor 2 in CHO cells using [3H]-NKA as radioligand				Bioorg Med Chem Lett 12: 2355-8 (2002) BindingDB Entry DOI: 10.7270/Q26T0KXW
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50116746 (3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)...) Show SMILES CCN(C\C(=N/OC)[C@H](CCN1CCC(CC1)n1c2ccccc2n(Cc2ccccn2)c1=O)c1ccc(Cl)c(Cl)c1)C(=O)c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C39H40Cl4N6O3/c1-3-47(38(50)27-20-28(40)23-29(41)21-27)25-35(45-52-2)32(26-11-12-33(42)34(43)22-26)15-19-46-17-13-31(14-18-46)49-37-10-5-4-9-36(37)48(39(49)51)24-30-8-6-7-16-44-30/h4-12,16,20-23,31-32H,3,13-15,17-19,24-25H2,1-2H3/b45-35+/t32-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	312	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity against recombinant human tachykinin receptor 3 in CHO cells using [125I]-[MePhe]-NKB as radioligand				Bioorg Med Chem Lett 12: 2355-8 (2002) BindingDB Entry DOI: 10.7270/Q26T0KXW
					More data for this Ligand-Target Pair