BDBM50116764 3-[1-Pyridin-2-yl-meth-(Z)-ylidene]-6-[1-[4-(3-pyridin-3-yl-propoxy)-phenyl]-meth-(Z)-ylidene]-piperazine-2,5-dione::CHEMBL77246

SMILES: O=c1[nH]\c(=C/c2ccccn2)c(=O)[nH]\c1=C/c1ccc(OCCCc2cccnc2)cc1

InChI Key: InChIKey=BJERXUSOIKLRIV-OZKZUFLSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50116764   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasminogen activator inhibitor-1 (Homo sapiens (Human))	BDBM50116764 (3-[1-Pyridin-2-yl-meth-(Z)-ylidene]-6-[1-[4-(3-pyr...) Show SMILES O=c1[nH]\c(=C/c2ccccn2)c(=O)[nH]\c1=C/c1ccc(OCCCc2cccnc2)cc1 Show InChI InChI=1S/C25H22N4O3/c30-24-22(28-25(31)23(29-24)16-20-7-1-2-13-27-20)15-18-8-10-21(11-9-18)32-14-4-6-19-5-3-12-26-17-19/h1-3,5,7-13,15-17H,4,6,14H2,(H,28,31)(H,29,30)/b22-15-,23-16-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Ltd. Curated by ChEMBL					Assay Description Inhibitory concentration required against Plasminogen activator inhibitor 1.				Bioorg Med Chem Lett 12: 2367-70 (2002) BindingDB Entry DOI: 10.7270/Q2319V6B
					More data for this Ligand-Target Pair