BDBM50117813 CHEMBL3613946::US9505753, 5o

SMILES: Oc1nn(CCc2ccc(cc2)-c2ccccc2)c(=O)[nH]c1=O

InChI Key: InChIKey=DJMUHYRXTADHBS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50117813   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D-amino-acid oxidase (Homo sapiens (Human))	BDBM50117813 (CHEMBL3613946 | US9505753, 5o) Show SMILES Oc1nn(CCc2ccc(cc2)-c2ccccc2)c(=O)[nH]c1=O Show InChI InChI=1S/C17H15N3O3/c21-15-16(22)19-20(17(23)18-15)11-10-12-6-8-14(9-7-12)13-4-2-1-3-5-13/h1-9H,10-11H2,(H,19,22)(H,18,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Johns Hopkins University Curated by ChEMBL					Assay Description Inhibition of recombinant human DAAO expressed in HEK cells using D-serine as substrate assessed as formation of alpha-keto acid, ammonia, hydrogen p...				J Med Chem 58: 7258-72 (2015) BindingDB Entry DOI: 10.7270/Q2SF2XZQ
					More data for this Ligand-Target Pair
D-amino-acid oxidase (Homo sapiens (Human))	BDBM50117813 (CHEMBL3613946 | US9505753, 5o) Show SMILES Oc1nn(CCc2ccc(cc2)-c2ccccc2)c(=O)[nH]c1=O Show InChI InChI=1S/C17H15N3O3/c21-15-16(22)19-20(17(23)18-15)11-10-12-6-8-14(9-7-12)13-4-2-1-3-5-13/h1-9H,10-11H2,(H,19,22)(H,18,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	8.5	25
THE JOHNS HOPKINS UNIVERSITY US Patent					Assay Description A reliable 96-well plate D-amino acid oxidase (DAAO) assay was developed based on previously published reports (J. Biol. Chem. 277: 27782 (2002)). Br...				US Patent US9505753 (2016) BindingDB Entry DOI: 10.7270/Q21J98QK
					More data for this Ligand-Target Pair