BDBM50117865 CHEMBL3614033
SMILES: Clc1ccc(cc1)-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
InChI Key: InChIKey=QFRWAGSZXCQHBD-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphodiesterase 3 (PDE3) (Homo sapiens (Human)) | BDBM50117865 (CHEMBL3614033) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
DaQing Oil Field General Hospital Curated by ChEMBL | Assay Description Inhibition of human PDE3A using FAM-cAMP by fluorescence polarization assay | Bioorg Med Chem 23: 6111-7 (2015) BindingDB Entry DOI: 10.7270/Q2HT2R46 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-inhibited 3',5'-cyclic phosphodiesterase B (Homo sapiens (Human)) | BDBM50117865 (CHEMBL3614033) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
DaQing Oil Field General Hospital Curated by ChEMBL | Assay Description Inhibition of human PDE3B using FAM-cAMP by fluorescence polarization assay | Bioorg Med Chem 23: 6111-7 (2015) BindingDB Entry DOI: 10.7270/Q2HT2R46 | |||||||||||
More data for this Ligand-Target Pair |