BDBM50117870 CHEMBL3614041

SMILES: Cc1cccc(c1)-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1

InChI Key: InChIKey=CHMBXISHNYTOKL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50117870   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-inhibited 3',5'-cyclic phosphodiesterase B (Homo sapiens (Human))	BDBM50117870 (CHEMBL3614041) Show SMILES Cc1cccc(c1)-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1 Show InChI InChI=1S/C14H11N7S/c1-9-3-2-4-10(5-9)12-8-22-14(16-12)21-7-11(6-15-21)13-17-19-20-18-13/h2-8H,1H3,(H,17,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
DaQing Oil Field General Hospital Curated by ChEMBL					Assay Description Inhibition of human PDE3B using FAM-cAMP by fluorescence polarization assay				Bioorg Med Chem 23: 6111-7 (2015) BindingDB Entry DOI: 10.7270/Q2HT2R46
					More data for this Ligand-Target Pair
Phosphodiesterase 3 (PDE3) (Homo sapiens (Human))	BDBM50117870 (CHEMBL3614041) Show SMILES Cc1cccc(c1)-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1 Show InChI InChI=1S/C14H11N7S/c1-9-3-2-4-10(5-9)12-8-22-14(16-12)21-7-11(6-15-21)13-17-19-20-18-13/h2-8H,1H3,(H,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	9.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
DaQing Oil Field General Hospital Curated by ChEMBL					Assay Description Inhibition of human PDE3A using FAM-cAMP by fluorescence polarization assay				Bioorg Med Chem 23: 6111-7 (2015) BindingDB Entry DOI: 10.7270/Q2HT2R46
					More data for this Ligand-Target Pair