BDBM50117932 (+/-)4-{2-[4-(9-bromo-4-chloro-1-methyl-3,6,7,12-tetrahydropyrido[2',3':4,5]cyclohepta[e]indol-12-yliden)hexahydro-1-pyridinyl]-2-oxoethyl}-1-pyridiniumolate::CHEMBL338930

SMILES: Cc1c[nH]c2c(Cl)cc3CCc4cc(Br)cnc4C(=C4CCN(CC4)C(=O)Cc4cc[n+]([O-])cc4)c3c12

InChI Key: InChIKey=HWYWVGSBHACYHO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50117932   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) Chain B (Homo sapiens (Human))	BDBM50117932 ((+/-)4-{2-[4-(9-bromo-4-chloro-1-methyl-3,6,7,12-t...) Show SMILES Cc1c[nH]c2c(Cl)cc3CCc4cc(Br)cnc4C(=C4CCN(CC4)C(=O)Cc4cc[n+]([O-])cc4)c3c12 |(13.66,-11.28,;13.26,-9.8,;14.73,-10.3,;15.66,-9.06,;14.77,-7.79,;15.1,-6.28,;16.57,-5.82,;13.96,-5.23,;12.49,-5.69,;11.53,-4.49,;9.99,-4.49,;9.04,-5.7,;7.57,-5.27,;6.45,-6.32,;4.98,-5.88,;6.81,-7.82,;8.27,-8.26,;9.39,-7.21,;10.76,-7.86,;10.76,-9.4,;12.09,-10.18,;12.09,-11.72,;10.76,-12.48,;9.45,-11.72,;9.45,-10.18,;10.76,-14.02,;9.43,-14.79,;12.11,-14.79,;12.11,-16.33,;10.76,-17.1,;10.76,-18.64,;12.09,-19.41,;12.09,-20.95,;13.44,-18.63,;13.42,-17.09,;12.16,-7.19,;13.28,-8.24,)| Show InChI InChI=1S/C29H26BrClN4O2/c1-17-15-32-29-23(31)14-20-2-3-21-13-22(30)16-33-28(21)27(26(20)25(17)29)19-6-8-34(9-7-19)24(36)12-18-4-10-35(37)11-5-18/h4-5,10-11,13-16,32H,2-3,6-9,12H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-val				J Med Chem 45: 3854-64 (2002) BindingDB Entry DOI: 10.7270/Q2TD9WPB
					More data for this Ligand-Target Pair