BDBM50117936 (+)4-(2-{4-[4-chloro-1-propyl-(12R)-3,6,7,12-tetrahydropyrido[2',3':4,5]cyclohepta[e]indol-12-yl]hexahydro-1-pyridinyl}-2-oxoethyl)-1-pyridiniumolate::(-)4-(2-{4-[4-chloro-1-propyl-(12R)-3,6,7,12-tetrahydropyrido[2',3':4,5]cyclohepta[e]indol-12-yl]hexahydro-1-pyridinyl}-2-oxoethyl)-1-pyridiniumolate::CHEMBL339026

SMILES: CCCc1c[nH]c2c(Cl)cc3CCc4cccnc4[C@H](C4CCN(CC4)C(=O)Cc4cc[n+]([O-])cc4)c3c12

InChI Key: InChIKey=NCXYOUKRMKDMLX-MUUNZHRXSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50117936   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) Chain B (Homo sapiens (Human))	BDBM50117936 ((+)4-(2-{4-[4-chloro-1-propyl-(12R)-3,6,7,12-tetra...) Show SMILES CCCc1c[nH]c2c(Cl)cc3CCc4cccnc4[C@H](C4CCN(CC4)C(=O)Cc4cc[n+]([O-])cc4)c3c12 Show InChI InChI=1S/C31H33ClN4O2/c1-2-4-24-19-34-31-25(32)18-23-7-6-22-5-3-12-33-30(22)28(27(23)29(24)31)21-10-13-35(14-11-21)26(37)17-20-8-15-36(38)16-9-20/h3,5,8-9,12,15-16,18-19,21,28,34H,2,4,6-7,10-11,13-14,17H2,1H3/t28-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-val				J Med Chem 45: 3854-64 (2002) BindingDB Entry DOI: 10.7270/Q2TD9WPB
					More data for this Ligand-Target Pair
Protein Farnesyltransferase (PFT) Chain B (Homo sapiens (Human))	BDBM50117936 ((+)4-(2-{4-[4-chloro-1-propyl-(12R)-3,6,7,12-tetra...) Show SMILES CCCc1c[nH]c2c(Cl)cc3CCc4cccnc4[C@H](C4CCN(CC4)C(=O)Cc4cc[n+]([O-])cc4)c3c12 Show InChI InChI=1S/C31H33ClN4O2/c1-2-4-24-19-34-31-25(32)18-23-7-6-22-5-3-12-33-30(22)28(27(23)29(24)31)21-10-13-35(14-11-21)26(37)17-20-8-15-36(38)16-9-20/h3,5,8-9,12,15-16,18-19,21,28,34H,2,4,6-7,10-11,13-14,17H2,1H3/t28-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>190	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-val				J Med Chem 45: 3854-64 (2002) BindingDB Entry DOI: 10.7270/Q2TD9WPB
					More data for this Ligand-Target Pair