BDBM50117992 (6,7-Diethoxy-quinazolin-4-yl)-(3-pyrimidin-5-yl-phenyl)-amine::CHEMBL126974

SMILES: CCOc1cc2ncnc(Nc3cccc(c3)-c3cncnc3)c2cc1OCC

InChI Key: InChIKey=OCPACVFCWMESLD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50117992   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50117992 ((6,7-Diethoxy-quinazolin-4-yl)-(3-pyrimidin-5-yl-p...) Show SMILES CCOc1cc2ncnc(Nc3cccc(c3)-c3cncnc3)c2cc1OCC Show InChI InChI=1S/C22H21N5O2/c1-3-28-20-9-18-19(10-21(20)29-4-2)25-14-26-22(18)27-17-7-5-6-15(8-17)16-11-23-13-24-12-16/h5-14H,3-4H2,1-2H3,(H,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description Inhibition of (EGFR) epidermal growth factor receptor tyrosine kinase				J Med Chem 45: 3865-77 (2002) BindingDB Entry DOI: 10.7270/Q2PN94Z0
					More data for this Ligand-Target Pair