BDBM50118122 CHEMBL3612325

SMILES: FC(F)(F)c1cccc(NC(=O)Nc2ccc(Sc3ccnc4ccsc34)cc2)c1

InChI Key: InChIKey=JNVNQHRESUUXEI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50118122   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50118122 (CHEMBL3612325) Show SMILES FC(F)(F)c1cccc(NC(=O)Nc2ccc(Sc3ccnc4ccsc34)cc2)c1 Show InChI InChI=1S/C21H14F3N3OS2/c22-21(23,24)13-2-1-3-15(12-13)27-20(28)26-14-4-6-16(7-5-14)30-18-8-10-25-17-9-11-29-19(17)18/h1-12H,(H2,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	988	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Minho Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using Tyr1 peptide as substrate after 1 hr by FRET-based assay in presence of 10 uM ATP				Bioorg Med Chem 23: 6497-509 (2015) BindingDB Entry DOI: 10.7270/Q27946G5
					More data for this Ligand-Target Pair