BDBM50118169 CHEMBL3613161
SMILES: [O-][N+](=O)c1cccc(Cn2nc(Oc3ccccc3)oc2=O)c1
InChI Key: InChIKey=CIWWJOCCTQXUNF-UHFFFAOYSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Monoglyceride lipase (Homo sapiens (Human)) | BDBM50118169 (CHEMBL3613161) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Eastern Finland Curated by ChEMBL | Assay Description Inhibition of human MAGL expressed in HEK293 cells pre-incubated for 10 mins before 2-AG substrate addition by HPLC method | Bioorg Med Chem 23: 6335-45 (2015) BindingDB Entry DOI: 10.7270/Q2NP266B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM50118169 (CHEMBL3613161) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Eastern Finland Curated by ChEMBL | Assay Description Inhibition of human ABHD6 expressed in HEK293 cells assessed as reduction in glycerol production from 1-AG hydrolysis pre-incubated for 30 mins befor... | Bioorg Med Chem 23: 6335-45 (2015) BindingDB Entry DOI: 10.7270/Q2NP266B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM50118169 (CHEMBL3613161) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Eastern Finland Curated by ChEMBL | Assay Description Inhibition of human ABHD6 expressed in HEK293 cells assessed as reduction in glycerol production from 1-AG hydrolysis pre-incubated for 30 mins befor... | Bioorg Med Chem 23: 6335-45 (2015) BindingDB Entry DOI: 10.7270/Q2NP266B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Homo sapiens (Human)) | BDBM50118169 (CHEMBL3613161) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Eastern Finland Curated by ChEMBL | Assay Description Inhibition of human MAGL expressed in HEK293 cells pre-incubated for 10 mins before 2-AG substrate addition by HPLC method | Bioorg Med Chem 23: 6335-45 (2015) BindingDB Entry DOI: 10.7270/Q2NP266B | |||||||||||
More data for this Ligand-Target Pair |