BDBM50118246 3-(3,4-Dimethoxy-phenyl)-2-[5-(3,4-dimethoxy-phenyl)-pyrimidin-2-yl]-1,2,3,4-tetrahydro-pyrrolo[3,4-b]quinolin-9-one::CHEMBL130612

SMILES: COc1ccc(cc1OC)C1N(Cc2c1nc1ccccc1c2O)c1ncc(cn1)-c1ccc(OC)c(OC)c1

InChI Key: InChIKey=PFSAOBZGNQDTPJ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50118246   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50118246 (3-(3,4-Dimethoxy-phenyl)-2-[5-(3,4-dimethoxy-pheny...) Show SMILES COc1ccc(cc1OC)C1N(Cc2c1nc1ccccc1c2O)c1ncc(cn1)-c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C31H28N4O5/c1-37-24-11-9-18(13-26(24)39-3)20-15-32-31(33-16-20)35-17-22-28(34-23-8-6-5-7-21(23)30(22)36)29(35)19-10-12-25(38-2)27(14-19)40-4/h5-16,29H,17H2,1-4H3,(H,34,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Phosphodiesterase 5 activity of human corpus cavernosum				J Med Chem 45: 4094-6 (2002) BindingDB Entry DOI: 10.7270/Q2R49RGM
					More data for this Ligand-Target Pair