BDBM50118486 CHEMBL3617058

SMILES: Cc1nocc1C(=O)Nc1cnc(c(N)n1)-c1cc(Cl)cc(Cl)c1Cl

InChI Key: InChIKey=UBQLVMPNILRISI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50118486   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50118486 (CHEMBL3617058) Show SMILES Cc1nocc1C(=O)Nc1cnc(c(N)n1)-c1cc(Cl)cc(Cl)c1Cl Show InChI InChI=1S/C15H10Cl3N5O2/c1-6-9(5-25-23-6)15(24)22-11-4-20-13(14(19)21-11)8-2-7(16)3-10(17)12(8)18/h2-5H,1H3,(H3,19,21,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	417	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of tetrodotoxin-sensitive NaV1.8 channel in human SHSY-5Y cells				J Med Chem 58: 7093-118 (2015) BindingDB Entry DOI: 10.7270/Q2XS5X6P
					More data for this Ligand-Target Pair