BDBM50118680 CHEMBL61039

SMILES: CCCCN(C)C[C@H](CC1CCCCC1)NC(=O)[C@H](CC(C)C)NC(=O)Cc1ccccc1

InChI Key: InChIKey=QDKGZMNFRRRHHF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50118680   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Presenilin-1 (Homo sapiens (Human))	BDBM50118680 (CHEMBL61039) Show SMILES CCCCN(C)C[C@H](CC1CCCCC1)NC(=O)[C@H](CC(C)C)NC(=O)Cc1ccccc1 Show InChI InChI=1S/C17H18FN3/c1-19-7-9-20(10-8-19)17-12-13-11-14(18)4-5-15(13)21-6-2-3-16(17)21/h2-6,11-12H,7-10H2,1H3	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta production				Bioorg Med Chem Lett 14: 1917-21 (2004) BindingDB Entry DOI: 10.7270/Q2TT4T4K
					More data for this Ligand-Target Pair