BDBM50119373 (2S)-2-amino-3-(1H-imidazol-4-yl)-N-[(2R)-1-{1-methanesulfonyl-1,2-dihydrospiro[indole-3,4'-piperidine]-1'-yl}-3-(naphthalen-2-yl)-1-oxopropan-2-yl]propanamide::1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {1-(4-chloro-benzyl)-2-[4-cyclohexyl-4-(2-methyl-2H-tetrazol-5-ylmethyl)-piperidin-1-yl]-2-oxo-ethyl}-amide::CHEMBL140155

SMILES: CS(=O)(=O)N1CC2(CCN(CC2)C(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@@H](N)Cc2cnc[nH]2)c2ccccc12

InChI Key: InChIKey=CNEVNNMBIGDVSA-WUFINQPMSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50119373   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50119373 ((2S)-2-amino-3-(1H-imidazol-4-yl)-N-[(2R)-1-{1-met...) Show SMILES CS(=O)(=O)N1CC2(CCN(CC2)C(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@@H](N)Cc2cnc[nH]2)c2ccccc12 Show InChI InChI=1S/C32H36N6O4S/c1-43(41,42)38-20-32(26-8-4-5-9-29(26)38)12-14-37(15-13-32)31(40)28(36-30(39)27(33)18-25-19-34-21-35-25)17-22-10-11-23-6-2-3-7-24(23)16-22/h2-11,16,19,21,27-28H,12-15,17-18,20,33H2,1H3,(H,34,35)(H,36,39)/t27-,28+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	108	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Agonist activity at human MC4 receptor expressed in HEK293 cells assessed as stimulation of cAMP production				J Med Chem 47: 6821-30 (2004) Article DOI: 10.1021/jm049278i BindingDB Entry DOI: 10.7270/Q2610ZSQ
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50119373 ((2S)-2-amino-3-(1H-imidazol-4-yl)-N-[(2R)-1-{1-met...) Show SMILES CS(=O)(=O)N1CC2(CCN(CC2)C(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@@H](N)Cc2cnc[nH]2)c2ccccc12 Show InChI InChI=1S/C32H36N6O4S/c1-43(41,42)38-20-32(26-8-4-5-9-29(26)38)12-14-37(15-13-32)31(40)28(36-30(39)27(33)18-25-19-34-21-35-25)17-22-10-11-23-6-2-3-7-24(23)16-22/h2-11,16,19,21,27-28H,12-15,17-18,20,33H2,1H3,(H,34,35)(H,36,39)/t27-,28+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	108	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Evaluated for Functional Activity at Melanocortin-4 receptor as effective concentration at 50% maximum CMP accumulation				J Med Chem 45: 4589-93 (2002) BindingDB Entry DOI: 10.7270/Q2GT5MH9
					More data for this Ligand-Target Pair