BDBM50119463 1-(4-Chloro-phenyl)-4-(1,2-diphenyl-1H-imidazol-4-ylmethyl)-piperazine::CHEMBL356068

SMILES: Clc1ccc(cc1)N1CCN(Cc2cn(c(n2)-c2ccccc2)-c2ccccc2)CC1

InChI Key: InChIKey=VVXPDQWPTOGEHG-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50119463   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50119463 (1-(4-Chloro-phenyl)-4-(1,2-diphenyl-1H-imidazol-4-...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2cn(c(n2)-c2ccccc2)-c2ccccc2)CC1 Show InChI InChI=1S/C26H25ClN4/c27-22-11-13-24(14-12-22)30-17-15-29(16-18-30)19-23-20-31(25-9-5-2-6-10-25)26(28-23)21-7-3-1-4-8-21/h1-14,20H,15-19H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Sassari Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine 1A receptor fof rat cerebral cortex using [3H]8-OH-DPAT as radioligand				J Med Chem 45: 4655-68 (2002) BindingDB Entry DOI: 10.7270/Q21G0N0M
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50119463 (1-(4-Chloro-phenyl)-4-(1,2-diphenyl-1H-imidazol-4-...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2cn(c(n2)-c2ccccc2)-c2ccccc2)CC1 Show InChI InChI=1S/C26H25ClN4/c27-22-11-13-24(14-12-22)30-17-15-29(16-18-30)19-23-20-31(25-9-5-2-6-10-25)26(28-23)21-7-3-1-4-8-21/h1-14,20H,15-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	91.8	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Sassari Curated by ChEMBL					Assay Description In vitro binding affinity for Dopamine D2 receptor of rat using [3H]YM-09151 as radioligand				J Med Chem 45: 4655-68 (2002) BindingDB Entry DOI: 10.7270/Q21G0N0M
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50119463 (1-(4-Chloro-phenyl)-4-(1,2-diphenyl-1H-imidazol-4-...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2cn(c(n2)-c2ccccc2)-c2ccccc2)CC1 Show InChI InChI=1S/C26H25ClN4/c27-22-11-13-24(14-12-22)30-17-15-29(16-18-30)19-23-20-31(25-9-5-2-6-10-25)26(28-23)21-7-3-1-4-8-21/h1-14,20H,15-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	315	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Sassari Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine 2A receptor of rat cerebral cortex using [3H]ketanserin as radioligand				J Med Chem 45: 4655-68 (2002) BindingDB Entry DOI: 10.7270/Q21G0N0M
					More data for this Ligand-Target Pair