BDBM50119469 1-(1,2-Diphenyl-1H-imidazol-4-ylmethyl)-4-(2-ethoxy-phenyl)-piperazine::CHEMBL143744

SMILES: CCOc1ccccc1N1CCN(Cc2cn(c(n2)-c2ccccc2)-c2ccccc2)CC1

InChI Key: InChIKey=VVYABMSSBXSXFF-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50119469   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50119469 (1-(1,2-Diphenyl-1H-imidazol-4-ylmethyl)-4-(2-ethox...) Show SMILES CCOc1ccccc1N1CCN(Cc2cn(c(n2)-c2ccccc2)-c2ccccc2)CC1 Show InChI InChI=1S/C28H30N4O/c1-2-33-27-16-10-9-15-26(27)31-19-17-30(18-20-31)21-24-22-32(25-13-7-4-8-14-25)28(29-24)23-11-5-3-6-12-23/h3-16,22H,2,17-21H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	34.7	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Sassari Curated by ChEMBL					Assay Description In vitro binding affinity for Dopamine D2 receptor of rat using [3H]YM-09151 as radioligand				J Med Chem 45: 4655-68 (2002) BindingDB Entry DOI: 10.7270/Q21G0N0M
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50119469 (1-(1,2-Diphenyl-1H-imidazol-4-ylmethyl)-4-(2-ethox...) Show SMILES CCOc1ccccc1N1CCN(Cc2cn(c(n2)-c2ccccc2)-c2ccccc2)CC1 Show InChI InChI=1S/C28H30N4O/c1-2-33-27-16-10-9-15-26(27)31-19-17-30(18-20-31)21-24-22-32(25-13-7-4-8-14-25)28(29-24)23-11-5-3-6-12-23/h3-16,22H,2,17-21H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	172	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Sassari Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine 2A receptor of rat cerebral cortex using [3H]ketanserin as radioligand				J Med Chem 45: 4655-68 (2002) BindingDB Entry DOI: 10.7270/Q21G0N0M
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50119469 (1-(1,2-Diphenyl-1H-imidazol-4-ylmethyl)-4-(2-ethox...) Show SMILES CCOc1ccccc1N1CCN(Cc2cn(c(n2)-c2ccccc2)-c2ccccc2)CC1 Show InChI InChI=1S/C28H30N4O/c1-2-33-27-16-10-9-15-26(27)31-19-17-30(18-20-31)21-24-22-32(25-13-7-4-8-14-25)28(29-24)23-11-5-3-6-12-23/h3-16,22H,2,17-21H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	56.9	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Sassari Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine 1A receptor fof rat cerebral cortex using [3H]8-OH-DPAT as radioligand				J Med Chem 45: 4655-68 (2002) BindingDB Entry DOI: 10.7270/Q21G0N0M
					More data for this Ligand-Target Pair