BDBM50119479 1-[1,2-Bis-(4-fluoro-phenyl)-1H-imidazol-4-ylmethyl]-4-phenyl-piperazine::CHEMBL143218

SMILES: Fc1ccc(cc1)-c1nc(CN2CCN(CC2)c2ccccc2)cn1-c1ccc(F)cc1

InChI Key: InChIKey=OCPUMUSLGLBFKT-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50119479   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50119479 (1-[1,2-Bis-(4-fluoro-phenyl)-1H-imidazol-4-ylmethy...) Show SMILES Fc1ccc(cc1)-c1nc(CN2CCN(CC2)c2ccccc2)cn1-c1ccc(F)cc1 Show InChI InChI=1S/C26H24F2N4/c27-21-8-6-20(7-9-21)26-29-23(19-32(26)25-12-10-22(28)11-13-25)18-30-14-16-31(17-15-30)24-4-2-1-3-5-24/h1-13,19H,14-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	167	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Sassari Curated by ChEMBL					Assay Description In vitro binding affinity for Dopamine D2 receptor of rat using [3H]YM-09151 as radioligand				J Med Chem 45: 4655-68 (2002) BindingDB Entry DOI: 10.7270/Q21G0N0M
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50119479 (1-[1,2-Bis-(4-fluoro-phenyl)-1H-imidazol-4-ylmethy...) Show SMILES Fc1ccc(cc1)-c1nc(CN2CCN(CC2)c2ccccc2)cn1-c1ccc(F)cc1 Show InChI InChI=1S/C26H24F2N4/c27-21-8-6-20(7-9-21)26-29-23(19-32(26)25-12-10-22(28)11-13-25)18-30-14-16-31(17-15-30)24-4-2-1-3-5-24/h1-13,19H,14-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	783	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Sassari Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine 2A receptor of rat cerebral cortex using [3H]ketanserin as radioligand				J Med Chem 45: 4655-68 (2002) BindingDB Entry DOI: 10.7270/Q21G0N0M
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50119479 (1-[1,2-Bis-(4-fluoro-phenyl)-1H-imidazol-4-ylmethy...) Show SMILES Fc1ccc(cc1)-c1nc(CN2CCN(CC2)c2ccccc2)cn1-c1ccc(F)cc1 Show InChI InChI=1S/C26H24F2N4/c27-21-8-6-20(7-9-21)26-29-23(19-32(26)25-12-10-22(28)11-13-25)18-30-14-16-31(17-15-30)24-4-2-1-3-5-24/h1-13,19H,14-18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	525	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Sassari Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine 1A receptor fof rat cerebral cortex using [3H]8-OH-DPAT as radioligand				J Med Chem 45: 4655-68 (2002) BindingDB Entry DOI: 10.7270/Q21G0N0M
					More data for this Ligand-Target Pair