BDBM50119486 1-(4-Methoxy-phenyl)-1H-pyrazole-3,5-dicarboxylic acid 3-benzhydryl-amide 5-benzylamide::CHEMBL341694

SMILES: COc1ccc(cc1)-n1nc(cc1C(=O)NCc1ccccc1)C(=O)NC(c1ccccc1)c1ccccc1

InChI Key: InChIKey=OLCHJSJDVYWASV-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50119486   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50119486 (1-(4-Methoxy-phenyl)-1H-pyrazole-3,5-dicarboxylic ...) Show SMILES COc1ccc(cc1)-n1nc(cc1C(=O)NCc1ccccc1)C(=O)NC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C32H28N4O3/c1-39-27-19-17-26(18-20-27)36-29(32(38)33-22-23-11-5-2-6-12-23)21-28(35-36)31(37)34-30(24-13-7-3-8-14-24)25-15-9-4-10-16-25/h2-21,30H,22H2,1H3,(H,33,38)(H,34,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of dihydroorotate dehydrogenase (DHODase) of Helicobacter pylori				J Med Chem 45: 4669-78 (2002) BindingDB Entry DOI: 10.7270/Q2C24VSW
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50119486 (1-(4-Methoxy-phenyl)-1H-pyrazole-3,5-dicarboxylic ...) Show SMILES COc1ccc(cc1)-n1nc(cc1C(=O)NCc1ccccc1)C(=O)NC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C32H28N4O3/c1-39-27-19-17-26(18-20-27)36-29(32(38)33-22-23-11-5-2-6-12-23)21-28(35-36)31(37)34-30(24-13-7-3-8-14-24)25-15-9-4-10-16-25/h2-21,30H,22H2,1H3,(H,33,38)(H,34,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human dihydroorotate dehydrogenase (DHODase)				J Med Chem 45: 4669-78 (2002) BindingDB Entry DOI: 10.7270/Q2C24VSW
					More data for this Ligand-Target Pair