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BDBM50119655 CHEMBL3616508

SMILES: On1c(=O)[nH]c2ncn(Cc3cccnc3)c2c1=O

InChI Key: InChIKey=ALBGHTKLFNLZMH-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50119655   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Poly(A)-specific ribonuclease (PARN)


(Homo sapiens (Human))
BDBM50119655
PNG
(CHEMBL3616508)
Show SMILES On1c(=O)[nH]c2ncn(Cc3cccnc3)c2c1=O
Show InChI InChI=1S/C11H9N5O3/c17-10-8-9(14-11(18)16(10)19)13-6-15(8)5-7-2-1-3-12-4-7/h1-4,6,19H,5H2,(H,14,18)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 1.25E+5n/an/an/an/an/an/a



University of Nottingham

Curated by ChEMBL


Assay Description
Inhibition of PARN (unknown origin)


Bioorg Med Chem Lett 25: 4219-24 (2015)


BindingDB Entry DOI: 10.7270/Q2BV7JFF
More data for this
Ligand-Target Pair
CCR4-NOT transcription complex subunit 7


(Homo sapiens (Human))
BDBM50119655
PNG
(CHEMBL3616508)
Show SMILES On1c(=O)[nH]c2ncn(Cc3cccnc3)c2c1=O
Show InChI InChI=1S/C11H9N5O3/c17-10-8-9(14-11(18)16(10)19)13-6-15(8)5-7-2-1-3-12-4-7/h1-4,6,19H,5H2,(H,14,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 6.60E+3n/an/an/an/an/an/a



University of Nottingham

Curated by ChEMBL


Assay Description
Inhibition of human poly(A)-selective ribonuclease Caf1 by fluorescence-based assay


Bioorg Med Chem Lett 25: 4219-24 (2015)


BindingDB Entry DOI: 10.7270/Q2BV7JFF
More data for this
Ligand-Target Pair