BDBM50119832 4-(6-Amino-purin-9-yl)-N-hydroxy-butyramide::CHEMBL302708

SMILES: Nc1ncnc2n(CCCC(=O)NO)cnc12

InChI Key: InChIKey=FQHHMZUDETYNCA-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50119832   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenylate cyclase (Homo sapiens (Human))	BDBM50119832 (4-(6-Amino-purin-9-yl)-N-hydroxy-butyramide | CHEM...) Show SMILES Nc1ncnc2n(CCCC(=O)NO)cnc12 Show InChI InChI=1S/C9H12N6O2/c10-8-7-9(12-4-11-8)15(5-13-7)3-1-2-6(16)14-17/h4-5,17H,1-3H2,(H,14,16)(H2,10,11,12)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human adenylate cyclase 5 expressed in HEK293 cells				Bioorg Med Chem Lett 12: 3085-8 (2002) BindingDB Entry DOI: 10.7270/Q2XW4J5B
					More data for this Ligand-Target Pair
Adenylate cyclase (Homo sapiens (Human))	BDBM50119832 (4-(6-Amino-purin-9-yl)-N-hydroxy-butyramide | CHEM...) Show SMILES Nc1ncnc2n(CCCC(=O)NO)cnc12 Show InChI InChI=1S/C9H12N6O2/c10-8-7-9(12-4-11-8)15(5-13-7)3-1-2-6(16)14-17/h4-5,17H,1-3H2,(H,14,16)(H2,10,11,12)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.				J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44
					More data for this Ligand-Target Pair
Adenylate cyclase (Homo sapiens (Human))	BDBM50119832 (4-(6-Amino-purin-9-yl)-N-hydroxy-butyramide | CHEM...) Show SMILES Nc1ncnc2n(CCCC(=O)NO)cnc12 Show InChI InChI=1S/C9H12N6O2/c10-8-7-9(12-4-11-8)15(5-13-7)3-1-2-6(16)14-17/h4-5,17H,1-3H2,(H,14,16)(H2,10,11,12)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against type V Adenyl Cyclase enzyme				Bioorg Med Chem Lett 12: 3089-92 (2002) BindingDB Entry DOI: 10.7270/Q2T43SFX
					More data for this Ligand-Target Pair