null
SMILES: Nc1ncnc2n(cnc12)[C@H]1C[C@H](OCC(O)=O)C=C1
InChI Key: InChIKey=CMJHWUKNQLPVPV-HTQZYQBOSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119853 (2-{[(1S,4S)-4-(6-amino-9H-purin-9-yl)cyclopent-2-e...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 7.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against Type V Adenyl Cyclase enzyme | Bioorg Med Chem Lett 12: 3089-92 (2002) BindingDB Entry DOI: 10.7270/Q2T43SFX | |||||||||||
More data for this Ligand-Target Pair |