BDBM50119893 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(7-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL107229

SMILES: Cc1cccc2CCN(C(=O)CN3CCN(Cc4ccc(Cl)cc4)CC3)c12

InChI Key: InChIKey=COJAZIUIZFFLJD-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50119893   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50119893 (2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(7-methyl...) Show SMILES Cc1cccc2CCN(C(=O)CN3CCN(Cc4ccc(Cl)cc4)CC3)c12 Show InChI InChI=1S/C22H26ClN3O/c1-17-3-2-4-19-9-10-26(22(17)19)21(27)16-25-13-11-24(12-14-25)15-18-5-7-20(23)8-6-18/h2-8H,9-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurogen Corporation Curated by ChEMBL					Assay Description Binding affinity towards human Dopamine Receptor D4 was determined via standard competitive displacement assays using [3H]-YM 09151 as radioligand				Bioorg Med Chem Lett 12: 3105-9 (2002) BindingDB Entry DOI: 10.7270/Q2JM2908
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50119893 (2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(7-methyl...) Show SMILES Cc1cccc2CCN(C(=O)CN3CCN(Cc4ccc(Cl)cc4)CC3)c12 Show InChI InChI=1S/C22H26ClN3O/c1-17-3-2-4-19-9-10-26(22(17)19)21(27)16-25-13-11-24(12-14-25)15-18-5-7-20(23)8-6-18/h2-8H,9-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.62E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurogen Corporation Curated by ChEMBL					Assay Description Binding affinity towards Alpha-1 adrenergic receptor via standard competitive displacement assay using rat brain homogenate with [3H]prazosin as radi...				Bioorg Med Chem Lett 12: 3105-9 (2002) BindingDB Entry DOI: 10.7270/Q2JM2908
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50119893 (2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(7-methyl...) Show SMILES Cc1cccc2CCN(C(=O)CN3CCN(Cc4ccc(Cl)cc4)CC3)c12 Show InChI InChI=1S/C22H26ClN3O/c1-17-3-2-4-19-9-10-26(22(17)19)21(27)16-25-13-11-24(12-14-25)15-18-5-7-20(23)8-6-18/h2-8H,9-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.62E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurogen Corporation Curated by ChEMBL					Assay Description Binding affinity towards human Dopamine receptor D2 was determined via standard competitive displacement assay using [3H]-YM 09151 as radioligand				Bioorg Med Chem Lett 12: 3105-9 (2002) BindingDB Entry DOI: 10.7270/Q2JM2908
					More data for this Ligand-Target Pair